Bisphenol-A is a well-studied chemical, known to cause developmental and reproductive harm. It was added to the Proposition 65 list of chemicals in 2015. BPA is mostly used to make polycarbonate plastic, epoxy resins and thermal paper. In addition, BPA may be used as dye-fixing agents for polyester and polyamide textiles. BPA can be used in the production of flame retardants, fungicides, antioxidants and in PVC production. It may also be used in spandex production for antistatic properties.

In May 2022, the first known settlement for socks made primarily of polyester with Spandex which contained BPA was finalized.

Traditionally, BPA is not considered a high-risk chemical in textile fibers. Previous Prop 65 settlements for BPA were for sunglasses, thermal paper, or other non-textile products. This is the first settlement involving a failure to warn consumers of the presence of BPA in socks made primarily of polyester with spandex. The possible exposure route for BPA in socks is dermal absorption directly through the skin when wearing and ingestion via hand-to-mouth contact after touching or handling.

Furthermore, it is observed that an increasing number of non-governmental organizations (NGOs) have initiated BPA studies on products including sports bras and athletic wear, etc.